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Interacting residues are labelled and shown as sticks

50 ZhaoJ.LuoD.LiangZ.LaoL.RongJ

Indeed, restoring the FMRP-CYFIP1 deficiency via a small chimeric peptide acting on the dysregulation of protein synthesis could be central for the new FXS pharmacological therapy development

We saw some improvement in disease severity but not enough to justify the risks for most patients. While the study showed that most patients should not undergo the procedure, the data hint that the benefits may outweigh the risks in some patients, such as those with exceptionally large clots

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In addition, activation of A2AR signaling using the A2AR-selective agonist CGS 21680 increased T cell survival with addition of exogenous GSH (Supplemental Figure 5, E and F)